Publications

ENaCt

Tyler AR, Ragbirsingh R, McMonagle CJ, Waddell PG, Heaps SE, Steed JW, Thaw P, Hall MJ, Probert MR. Encapsulated Nanodroplet Crystallization of Organic-Soluble Small Molecules. Chem. 2020, 6(7), 1755-1765.

Co-Crystallisation

Metherall JP, Corner PA, McCabe JF, Hall MJ, Probert MR. High-throughput nanoscale crystallization of di­hydro­pyridine active pharmaceutical ingredients. Acta Cryst. B 2023, 80(1), 4-12

Crystallisation Techniques

Metherall JP, Carroll RC, Coles SJ, Hall MJ, Probert MR. Advanced crystallisation methods for small organic moleculesChem. Soc. Rev. 2023, 52(6), 1995-2010.

Applications of ENaCT

Cooper MS, Zhang L, Ibrahim M, Zhang K, Sun X, Röske J, Göhl M, Brönstrup M, Cowell JK, Sauerhering L, Becker S, Vangeel L, Jochmans D, Neyts J, Rox K, Marsh GP, Maple HJ, Hilgenfeld R. Diastereomeric Resolution Yields Highly Potent Inhibitor of SARS-CoV-2 Main Protease. J. Med. Chem. 2022, 65, 19, 13328–13342

Zhu J, Moreno I,  Quinn P, Yufit DS, Song L, Young CM, Duan Z, Tyler AR, Waddell PG, Hall MJ, Probert MR, Smith AD, O’Donoghue AC. The Role of the Fused Ring in Bicyclic Triazolium Organocatalysts: Kinetic, X-ray and DFT Insights. J. Org. Chem. 2022, 87(6), 4241–4253

Al Subeh ZY, Waldbusser AL, Raja HA, Pearce CJ, Ho KL, Hall MJ,  Probert MR, Oberlies NH, Hematian S. Structural Diversity of Perylenequinones is Driven by their Redox Behavior. J. Org. Chem. 2022, 87(5), 2697–2710

Straker H, McMillian L, Mardiana L, Hebberd G, Watson E, Waddell PG, Probert MR, Hall MJ. Polymorph prediction through structural isomorphism and discovery of a new crystalline form of cannabidiolCryst. Eng. Comm. 2023, 25(16), 2479-2484.

High Pressure Crystallography

Taylor CR, Mulvee MT, Perenyi DS, Probert MR, Day GM, Steed JW. Minimizing Polymorphic Risk through Cooperative Computational and Experimental Exploration. J. Am. Chem. Soc. 2020, 142(39), 16668–16680

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